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In mathematics and science, a nonlinear system (or a non-linear system) is a system in which the change of the output is not proportional to the change of the input. [1] [2] Nonlinear problems are of interest to engineers, biologists, [3] [4] [5] physicists, [6] [7] mathematicians, and many other scientists since most systems are inherently nonlinear in nature. [8]
These systems are often very difficult to solve, so modeling of networks as a linear dynamical systems is easier. Linear systems contain no products between xs and are always solvable. They have the following form for all i: = + + + Unfortunately, biological systems are often nonlinear and therefore need nonlinear models.
System identification is a method of identifying or measuring the mathematical model of a system from measurements of the system inputs and outputs. The applications of system identification include any system where the inputs and outputs can be measured and include industrial processes, control systems, economic data, biology and the life sciences, medicine, social systems and many more.
Also, the output of a linear system can contain harmonics (and have a smaller fundamental frequency than the input) even when the input is a sinusoid. For example, consider a system described by () = (+ ()) (). It is linear because it satisfies the superposition principle.
Systems biology can be considered from a number of different aspects. As a field of study, particularly, the study of the interactions between the components of biological systems, and how these interactions give rise to the function and behavior of that system (for example, the enzymes and metabolites in a metabolic pathway or the heart beats).
The theory, which can be called a reaction–diffusion theory of morphogenesis, has become a basic model in theoretical biology. [2] Such patterns have come to be known as Turing patterns. For example, it has been postulated that the protein VEGFC can form Turing patterns to govern the formation of lymphatic vessels in the zebrafish embryo. [3]
Linear pathways follow a step-by-step sequence, where each enzymatic reaction results in the transformation of a substrate into an intermediate product. This intermediate is processed by subsequent enzymes until the final product is synthesized. A linear chain of four enzyme-catalyzed steps. A linear pathway can be studied in various ways.
The mediaeval great chain of being as a staircase, implying the possibility of progress: [1] Ramon Lull's Ladder of Ascent and Descent of the Mind, 1305. Alternatives to Darwinian evolution have been proposed by scholars investigating biology to explain signs of evolution and the relatedness of different groups of living things.