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Buprenorphine/naloxone, sold under the brand name Suboxone among others, is a fixed-dose combination medication that includes buprenorphine and naloxone. [3] It is used to treat opioid use disorder, and reduces the mortality of opioid use disorder by 50% (by reducing the risk of overdose on full-agonist opioids such as heroin or fentanyl).
Buprenorphine, sold under the brand name Subutex among others, is an opioid used to treat opioid use disorder, acute pain, and chronic pain. [18] It can be used under the tongue (sublingual), in the cheek (buccal), by injection (intravenous and subcutaneous), as a skin patch (transdermal), or as an implant.
On a community level, established safe injection sites that provide a hygienic space supervised by licensed healthcare professionals allow for safe monitoring of participants and provide health education and care to prevent overdose. Another way to help prevent overdose, especially regarding opioids, is the increased access and knowledge of ...
The consequence of relapse when weighing the best course of treatment for opiate use disorder remains a concern. Methadone and buprenorphine administration maintain greater drug tolerance while naltrexone allows tolerance to fade, leading to higher instances of an overdose in people who relapse and thus higher mortality.
More than 200 people in Mecklenburg County died from drug overdoses last year, according to data from the N.C. Department of Health and Human Services.
Prescribing naloxone should be accompanied by standard education that includes preventing, identifying, and responding to an overdose; rescue breathing; and calling emergency services. [24] Distribution of naloxone to individuals likely to encounter people who overdose is one aspect of harm reduction strategies. [25]
A new study from Case Western Reserve University School of Medicine reveals that popular diabetes and weight-loss drugs, Wegovy and Ozempic, may significantly reduce alcohol misuse and alcohol use ...
Opioid overdose leads to death when people stop breathing. [62] Bystanders trained in first aid can evaluate people who have overdosed and provide basic life support including rescue breathing via bag valve mask or mouth to mouth. If the person who has overdosed does not have a pulse, rescuers should begin CPR. [49]