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Drugs or pharmaceutical agents inducing ototoxicity are regarded as ototoxic medications. Anatomy of the human ear. There is a wide range of ototoxic medications, for example, antibiotics, antimalarials, chemotherapeutic agents, non-steroidal anti-inflammatory drugs (NSAIDs) and loop diuretics. [2]
Ototoxicity of gentamicin can be exploited to treat some individuals with Ménière's disease by destroying the inner ear, which stops the vertigo attacks but causes permanent deafness. [19] Due to the effects on mitochondria, certain inherited mitochondrial disorders result in increased sensitivity to the toxic effects of aminoglycosides.
Benign paroxysmal positional vertigo (BPPV) is a disorder arising from a problem in the inner ear. [3] Symptoms are repeated, brief periods of vertigo with movement, characterized by a spinning sensation upon changes in the position of the head. [1] This can occur with turning in bed or changing position. [3]
It can also be a sign of an inner ear infection or problems with blood supply to the inner ear. In some cases, vertigo may be a symptom of a stroke . Some additional causes of vertigo include:
The main symptoms are severe vertigo and nystagmus. The most common symptom of vestibular neuritis is the onset of vertigo that has formed from an ongoing infection or trauma. [9] The dizziness sensation that is associated with vertigo is thought to be from the inner ear labyrinth. [10]
Otitis interna, or labyrinthitis, involves the inner ear. The inner ear includes sensory organs for balance and hearing. When the inner ear is inflamed, vertigo is a common symptom. Other symptoms in adults include pain and drainage from ear or problems with hearing. [8] Symptoms in children can include excessive crying, touching at ears ...
However, these classifications are based on laboratory behavior. The development of antibiotics has had a profound effect on the health of people for many years. Also, both people and animals have used antibiotics to treat infections and diseases. In practice, both treat bacterial infections. [1]
Treatment-related adverse effects in AOE studies were determined in phase II and III trials. This includes ear pruritus, ear debris, superimposed ear infection, ear congestion, ear pain, and erythema. Similar effects were demonstrated in AOMT studies.
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