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A genetic predisposition on its own, without superimposed environmental risk factors, is not thought to give rise to schizophrenia. [4] [6] Environmental risk factors are many, and include pregnancy complications, prenatal stress and nutrition, and adverse childhood experiences. An environmental risk factor may act alone or in combination with ...
The causes of schizophrenia that underlie the development of schizophrenia, a psychiatric disorder, are complex and not clearly understood.A number of hypotheses including the dopamine hypothesis, and the glutamate hypothesis have been put forward in an attempt to explain the link between altered brain function and the symptoms and development of schizophrenia.
The causes of schizophrenia may include genetic and environmental factors. [7] Genetic factors include a variety of common and rare genetic variants . [ 21 ] Possible environmental factors include being raised in a city , childhood adversity, cannabis use during adolescence, infections, the age of a person's mother or father , and poor ...
Risk factors for mental illness include psychological trauma, adverse childhood experiences, genetic predisposition, and personality traits. [7] [8] Correlations between mental disorders and substance use are also found to have a two way relationship, in that substance use can lead to the development of mental disorders and having mental disorders can lead to substance use/abuse.
The epigenetics of schizophrenia is the study of how inherited epigenetic changes are regulated and modified by the environment and external factors and how these changes influence the onset and development of, and vulnerability to, schizophrenia. Epigenetics concerns the heritability of those changes, too.
Schizophrenia is caused by a combination of genetic and environmental factors. [6] Research illustrates that schizophrenia is hereditary and is more likely to strike those who carry particular genes. [9] It is believed that those who are susceptible to the disorder are affected by something in their environment.
The magnitude of the connection between cannabis and schizophrenia for young men surprised study author Volkow, who was expecting the number to be closer to 10%. “This is worrisome,” she said.
Some causes can contribute to these disorders like genetic factors (genetics, family medical history), [51] environmental factors (excessive stress, exposure to neurotoxins, pollution, viral infections, and bacterial infections), [52] [53] physical factors (traumatic brain injury, illness), [54] and prenatal factors (birth defects, exposure to ...
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