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Tenofovir disoproxil is a prodrug that is quickly absorbed from the gut and cleaved to release tenofovir. [10] Inside cells, tenofovir is phosphorylated to tenofovir diphosphate (which is analogous to a triphosphate, as tenofovir itself already has one phosphonate residue), the active compound that inhibits reverse transcriptase via chain ...
It does not cure HIV/AIDS. [5] Emtricitabine/tenofovir is taken by mouth. [7] Common side effects include headache, tiredness, trouble sleeping, abdominal pain, weight loss, and rash. [5] Serious side effects may include high blood lactate levels and enlargement of the liver. [7]
Tenofovir alafenamide, sold under the brand name Vemlidy, is an antiviral medication used against hepatitis B and HIV. It is used for the treatment of chronic ...
We explain five common types of arthritis, including symptoms and treatment. The specifics about different conditions that cause swelling in the joints. We explain five common types of arthritis ...
Underlying hepatitis B virus (HBV) can interact with emtricitabine to cause significant liver damage, but it does not have a significant detrimental effect on the liver when given to patients without HBV. [18] Tenofovir alafenamide (TAF) is a prodrug of tenofovir that functions as a nucleotide reverse transcriptase inhibitor (NtRTI). Other ...
Tenofovir, also known as TDF is a so-called 'prodrug' with the active compound deactivated by a molecular side chain that dissolves in the human body allowing a low dose of tenofovir to reach the site of desired activity. One example of the prodrug form is tenofovir disoproxil fumarate with the trade name Viread (Gilead Sciences Inc USA).
While there are over 100 types of arthritis and related conditions, Dr. Gendai Echezona, a fellowship-trained, triple board-certified anesthesiologist specializing in interventional pain ...
rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, psoriasis, Crohn's disease, ulcerative colitis Intetumumab [83] [84] mab: human: CD51: solid tumors (prostate cancer, melanoma) Inolimomab: mab: mouse: CD25 (α chain of IL-2 receptor) graft versus host disease: Inotuzumab ozogamicin [39] Besponsa: mab: humanized: CD22: Y: Acute ...