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Albendazole is a broad-spectrum antihelmintic and antiprotozoal agent of the benzimidazole type. [3] It is used for the treatment of a variety of intestinal parasite infections, including ascariasis, pinworm infection, hookworm infection, trichuriasis, strongyloidiasis, taeniasis, clonorchiasis, opisthorchiasis, cutaneous larva migrans, giardiasis, and gnathostomiasis, among other diseases.
In enzymology, an albendazole monooxygenase (EC 1.14.13.32) is an enzyme that catalyzes the chemical reaction. albendazole + NADPH + H + + O 2 albendazole S-oxide + NADP + + H 2 O. The four substrates of this enzyme are albendazole, NADPH, H +, and O 2, whereas its three products are albendazole S-oxide, NADP +, and H 2 O.
All major gastrointestinal nematode genera survived treatment in various studies. In cattle, prevalence of anthelminthic resistance varied between anthelmintic classes from 0–100% (benzimidazoles and macrocyclic lactones), 0–17% (levamisole) and 0–73% (moxidectin), and both Cooperia and Ostertagia survived treatment. [ 14 ]
This has a cost of about 2 to 3 cents per person per treatment. [1] This is known as mass drug administration and is often carried out among school-age children. [32] For this purpose, broad-spectrum benzimidazoles such as mebendazole and albendazole are the drugs of choice recommended by WHO. [33]
The Mayo Clinic diet, a program that adheres to this notion, was developed by medical professionals based on scientific research, so you can trust that this program is based on science, and not ...
Other drugs that can be effective are albendazole and thiabendazole (25 mg/kg twice daily for 5 days—400 mg maximum (generally)). [11] All patients who are at risk of disseminated strongyloidiasis should be treated. The optimal duration of treatment for patients with disseminated infections is not clear. [10]
Schistosomiasis caused by trematodes of the genus Schistosoma: [13] As of 2005, praziquantel is the primary treatment for human schistosomiasis, for which it is usually effective in a single dose. [14] Clonorchiasis brought on by the Chinese liver fluke Clonorchis sinensis [15]
Mayo Clinic Arizona is a multi-campus medical clinic and tertiary medical center in Phoenix, Arizona. Its two main campuses are the outpatient clinic building, situated in east Scottsdale, Arizona, and the Arizona Hospital, located in north Phoenix, Arizona. [ 1 ]
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109 S High St #100, Columbus, OH · Directions · (614) 224-4261