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Toxic megacolon; Other names: Megacolon toxicum: Micrograph of pseudomembranous colitis, a cause of toxic megacolon. H&E stain. Specialty: Gastroenterology: Symptoms: Swelling of the belly, Pain in the belly, Fever, Rapid heart rate, Shock, Diarrhea. [1] Complications: Septic shock, perforation of the colon: Risk factors: Chronic bowel disease ...
Perforation, toxic megacolon: Usual onset ~6-7 weeks after starting checkpoint inhibitor [1] Causes: Cancer immunotherapy treatment: Risk factors: Caucasian, NSAID use, anti-CTLA4 treatment, melanoma, history of prior checkpoint inhibitor induced colitis, Faecalibacterium in fecal microbiota: Diagnostic method: Colonoscopy, stool tests for ...
In patients with HIV/AIDS, cytomegalovirus (CMV) colitis is the leading cause of toxic megacolon and emergency laparotomy. CMV may also increase the risk of toxic megacolon in non-HIV/AIDS patients with IBD. [10]
Toxic megacolon is a state in which the colon is abnormally distended, ... Several risk factors are associated with eventual need for colectomy, including: prior ...
If an individual is not at high risk of colorectal cancer, then Medicare will cover screenings either every 120 months (10 years), or 48 months (4 years) after a person has a flexible sigmoidoscopy.
Ogilvie syndrome, or acute colonic pseudo-obstruction is the acute dilatation of the colon in the absence of any mechanical obstruction in severely ill patients. [1]Acute colonic pseudo-obstruction is characterized by massive dilatation of the cecum (diameter > 10 cm) and right colon on abdominal X-ray.
The NHS guidance states that lower risk of cancer is one of the long term benefits of drinking less alcohol. Factbox-Countries' guidance on alcohol consumption Skip to main content
The toxins are the main virulence factors produced by the gram positive, anaerobic, [2] Clostridioides difficile bacteria. The toxins function by damaging the intestinal mucosa and cause the symptoms of C. difficile infection, including pseudomembranous colitis. TcdA is one of the largest bacterial toxins known.