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  2. Folate deficiency - Wikipedia

    en.wikipedia.org/wiki/Folate_deficiency

    Signs of folate deficiency anemia most of the time are subtle. [4] Anemia (macrocytic, megaloblastic anemia) can be a sign of advanced folate deficiency in adults. [1] Folate deficiency anemia may result in feeling tired, weakness, changes to the color of the skin or hair, open sores on the mouth, shortness of breath, palpitations, lightheadedness, cold hands and feet, headaches, easy bleeding ...

  3. Methylenetetrahydrofolate reductase deficiency - Wikipedia

    en.wikipedia.org/wiki/Methylenetetrahydrofolate...

    A different study corroborates these results and suggests a physiological dose (800 μg) of 5-methyltetrahydrofolate can bypass MTHFR C677T and A1298C isoforms in couples with fertility problems. [16] This treatment with 5-MTHF also avoids un-metabolized folic acid syndrome, which can occur with folic acid intakes of 5 mg per day. [16]

  4. Folate - Wikipedia

    en.wikipedia.org/wiki/Folate

    Folate in the form of folic acid is used to treat anemia caused by folate deficiency. [3] Folic acid is also used as a supplement by women during pregnancy to reduce the risk of neural tube defects (NTDs) in the baby. [3] [10] NTDs include anencephaly and spina bifida, among other defects.

  5. Anemia in pregnancy - Wikipedia

    en.wikipedia.org/wiki/Anemia_in_pregnancy

    Vitamin B12: Women who consume strictly vegan diets are advised to take Vitamin B12 supplements; this helps prevent anemia due to low Vitamin B12 levels. [29] Folic Acid: Folic acid supplement recommended for women with history of documented folate deficiency. Folic acid supplementation also recommended for prevention of neural tube defects in ...

  6. Neural tube defect - Wikipedia

    en.wikipedia.org/wiki/Neural_tube_defect

    A deficiency of folate itself does not cause neural tube defects. The association seen between reduced neural tube defects and folic acid supplementation is due to a gene-environment interaction such as vulnerability caused by the C677T methylenetetrahydrofolate reductase (MTHFR) variant.

  7. Nutrition and pregnancy - Wikipedia

    en.wikipedia.org/wiki/Nutrition_and_pregnancy

    Folic acid, which is the synthetic form of the vitamin folate, is critical both in pre- and peri-conception. [7] Deficiencies in folic acid may cause neural tube defects (NTDs). Women who had 0.4 mg of folic acid in their systems due to supplementing 3 months before childbirth significantly reduced the risk of NTDs. [29]

  8. Flour to be fortified with folic acid from 2026 to tackle ...

    www.aol.com/flour-fortified-folic-acid-2026...

    The new legislation will require millers to add folic acid to non-wholemeal wheat flour from the end of 2026. Folic acid is a synthetic form of vitamin B9 and is also known as folate.

  9. Spina bifida - Wikipedia

    en.wikipedia.org/wiki/Spina_bifida

    Research has shown the lack of folic acid (folate) is a contributing factor in the pathogenesis of neural tube defects, including spina bifida. Supplementation of the mother's diet with folate can reduce the incidence of neural tube defects by about 70%, and can also decrease the severity of these defects when they occur.

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