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Ezetimibe, sold under the brand name Zetia among others, is a medication used to treat high blood cholesterol and certain other lipid abnormalities. [ 3 ] [ 4 ] Generally it is used together with dietary changes and a statin . [ 5 ]
It is a combination of ezetimibe (known as Zetia in the United States) and the statin drug simvastatin (known as Zocor in the US). Ezetimibe reduces blood cholesterol by acting at the brush border of the small intestine and inhibiting the absorption of cholesterol, leading to a decrease in the delivery of intestinal cholesterol to the liver.
The researchers collected sleep data using a questionnaire and a home-based sleep study (polysomnographic evaluation). In addition, the researchers measured the daytime blood pressure of the ...
What did the study find? The study analyzed data from nearly 10,000 people who were enrolled in a randomized clinical trial, looking into the impact of low-dose aspirin on reducing heart disease ...
Under conditions of moderate alcohol consumption where blood alcohol levels average 0.06–0.08% and decrease 0.01–0.02% per hour, an alcohol clearance rate of 4–5 hours would coincide with disruptions in sleep maintenance in the second half of an 8-hour sleep episode. [3]
Another study points out that there is no significant difference between the two classes of drugs in terms of adverse effects. [20] Unlike benzodiazepines, nonbenzodiazepines appear to have little or no impact on sleep stages and do not lead to rapid-eye-movement (REM) sleep rebound. [ 21 ]
The weight-loss drug Zepbound (tirzepatide) now has another major benefit: on Dec. 20, it became the first drug approved by the U.S. Food and Drug Administration (FDA) to treat obstructive sleep ...
The drug reaches peak concentration in about 2 hours and has a half-life in healthy adults of about 2–3 hours. [11] [9] [12] Zolpidem's half life is decreased in children and increased in the elderly and people with liver issues. While some studies show men metabolize zolpidem faster than women (possibly due to testosterone), [60] others do ...