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Doctor Octopus (Dr. Otto Octavius), also known as Doc Ock for short, is a fictional character appearing in American comic books published by Marvel Comics.The character was created by Stan Lee and Steve Ditko and first appeared in The Amazing Spider-Man #3 (July 1963).
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Lady Octopus (Carolyn Trainer), also known as Doctor Octopus II, is a supervillain appearing in American comic books published by Marvel Comics, primarily as an enemy to the superheroes Spider-Man and Scarlet Spider.
In the episode "Hobgoblin" Pt. 1, Doc Ock also places Spider-Man under mind control and has him join the team to make it the Sinister Six. However, Harry Osborn becomes the Hobgoblin and frees Spider-Man and the rest of the team from Doc Ock's control. All of the group's members are defeated and arrested by the end of the first season.
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While Peter is gone, Miles decides to build a robot that he names TWIST-E. However, TWIST-E goes haywire and causes destruction until Doc Ock steals it to reprogram it for evil. At Doc Ock's lair, Peter and Miles web up Doc Ock and leave her for the police to arrest. With Peter's help, TWIST-E is officially completed and becomes his Spider-Bot.
"Dying Wish" is a 2012 comic book storyline in The Amazing Spider-Man, published by Marvel Comics. The story began with a prologue in The Amazing Spider-Man #698 and ended in The Amazing Spider-Man #700, the final issue of that series, ending over fifty years of Marvel's publication of The Amazing Spider-Man.