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Zika fever (also known as Zika virus disease) is an illness caused by Zika virus. [80] Around 80% of cases are estimated to be asymptomatic, though the accuracy of this figure is hindered by the wide variance in data quality, and figures from different outbreaks can vary significantly. [ 81 ]
Zika fever, also known as Zika virus disease or simply Zika, is an infectious disease caused by the Zika virus. [1] Most cases have no symptoms, but when present they are usually mild and can resemble dengue fever .
A viral infection does not always cause disease. A viral infection simply involves viral replication in the host, but disease is the damage caused by viral multiplication. [5] An individual who has a viral infection but does not display disease symptoms is known as a carrier. [17] Mechanisms by which viruses cause damage and disease to host cells
Flavivirus, renamed Orthoflavivirus in 2023, [3] is a genus of positive-strand RNA viruses in the family Flaviviridae.The genus includes the West Nile virus, dengue virus, tick-borne encephalitis virus, yellow fever virus, Zika virus and several other viruses which may cause encephalitis, [4] as well as insect-specific flaviviruses (ISFs) such as cell fusing agent virus (CFAV), Palm Creek ...
The Flaviviridae are part of RNA virus supergroup II, which includes certain plant viruses and bacterial viruses. [2] The family has four genera: [1] [2] Genus Flavivirus, renamed Orthoflavivirus in 2023, (includes Dengue virus, Japanese encephalitis, Kyasanur Forest disease, Powassan virus, West Nile virus, Yellow fever virus, and Zika virus)
Transmission of the virus into humans can lead to a viral infection known as Spondweni fever, with symptoms that include headache, nausea, myalgia (muscle pain) and arthralgia (joint pain). [ 1 ] [ 3 ] However, as SPONV is phylogenetically close to the ZIKV, it is commonly misdiagnosed as ZIKV along with other viral illnesses.
Uganda The Zika virus is first isolated in 1947 in a rhesus monkey in the Zika Forest near Entebbe, Uganda, and first recovered from an Aedes africanus mosquito in 1948. [4] [5] Serological evidence indicates additional human exposure and/or presence in some mosquito species between 1951 and 1981 in parts of Africa (Uganda and Tanzania having the first detection of antibody in humans, in 1952 ...
Viral host tropism is determined by a combination of susceptibility and permissiveness: a host cell must be both permissive (allow viral replication) and susceptible (possess the receptor complement needed for viral entry) for a virus to establish infection. Once a virus binds to a host cell, the host cell must then provide the necessary ...