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Ovarian tissue autotransplantation may pose a risk of cancer recurrence in patients with colorectal, gastric and endometrial cancer. [8] However, no metastases have been detected in ovarian tissue from lymphoma and breast cancer patients who have been undergoing ovarian tissue cryopreseration. [8]
Ideally, the artificial ovary should contain follicles or oocytes obtained from ovarian tissue cryopreservation, as well as other ovarian cells to provide growth factors. [3] Isolated follicles are then transplanted (either at the normal site of the ovary or elsewhere in the body) in a delivery scaffold. [ 4 ]
The same study found that, of 65 patients referred to the program, 28% declined to undergo embryo, oocyte, or tissue cryopreservation. 9% were found not to be eligible for medical reasons. Of the remaining 41 patients, 85% chose to cryopreserve embryos, 10% chose to cryopreserve oocytes, and 5% chose to undergo ovarian tissue freezing. [9]
TVOR is typically performed after ovarian hyperstimulation, where oocytes are pharmacologically stimulated to mature. When the ovarian follicles have reached a certain degree of development, induction of final oocyte maturation is performed, generally by an intramuscular or subcutaneous injection of human chorionic gonadotropin (hCG). [10]
Assisted reproductive technology (ART) includes medical procedures used primarily to address infertility. This subject involves procedures such as in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), and cryopreservation of gametes and embryos, and the use of fertility medication.
Tissue samples like tumors and histological cross sections; Eggs in oocyte cryopreservation; Embryos at cleavage stage (that are 2, 4, 8 or 16 cells) or at early blastocyst stage, in embryo cryopreservation; Ovarian tissue in ovarian tissue cryopreservation; Plant seeds, callus, shoots tips or dormant buds are cryopreserved for conservation ...
Oocyte cryopreservation is a procedure to preserve a woman's eggs . The technique is often used to delay pregnancy. At the time pregnancy is desired, the eggs can be thawed, fertilized, and transferred to the uterus as embryos. Many studies have suggested infertility problems as germ cell deterioration related to aging. [1]
Cryopreservation of ovarian tissue, often called ovarian tissue cryopreservation, is of interest to women who want to preserve their reproductive function beyond the natural limit, or whose reproductive potential is threatened by cancer therapy, [48] for example in hematologic malignancies or breast cancer. [49]