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  2. Lymphocytopenia - Wikipedia

    en.wikipedia.org/wiki/Lymphocytopenia

    Lymphocytopenia is commonly caused by a recent infection, such as COVID-19. [3]Lymphocytopenia, but not idiopathic CD4+ lymphocytopenia, is associated with corticosteroid use, infections with HIV and other viral, bacterial, and fungal agents, malnutrition, systemic lupus erythematosus, [4] severe stress, [5] intense or prolonged physical exercise (due to cortisol release), [6] rheumatoid ...

  3. Reactive lymphocyte - Wikipedia

    en.wikipedia.org/wiki/Reactive_lymphocyte

    Reactive lymphocyte surrounded by red blood cells. In immunology, reactive lymphocytes, variant lymphocytes, atypical lymphocytes, Downey cells or Türk cells are cytotoxic (CD8 +) lymphocytes that become large as a result of antigen stimulation. Typically, they can be more than 30 μm in diameter with varying size and shape.

  4. Lymphoproliferative disorders - Wikipedia

    en.wikipedia.org/wiki/Lymphoproliferative_disorders

    Lymphoproliferative disorders are a set of disorders characterized by the abnormal proliferation of lymphocytes into a monoclonal lymphocytosis. The two major types of lymphocytes are B cells and T cells, which are derived from pluripotent hematopoietic stem cells in the bone marrow.

  5. ZAP70 - Wikipedia

    en.wikipedia.org/wiki/ZAP70

    Due to its role in lymphocyte signaling, ZAP-70 has been associated with several diseases affecting lymphocytes. ZAP-70 expression is a significant indicator of the survival of lymphocytes and has been notably associated with chronic lymphocytic leukemia (CLL). [11] CLL is a cancer that develops from overproduction of B cells in the bone marrow.

  6. Mucosa-associated lymphoid tissue - Wikipedia

    en.wikipedia.org/wiki/Mucosa-associated_lymphoid...

    The mucosa-associated lymphoid tissue (MALT), also called mucosa-associated lymphatic tissue, is a diffuse system of small concentrations of lymphoid tissue found in various submucosal membrane sites of the body, such as the gastrointestinal tract, nasopharynx, thyroid, breast, lung, salivary glands, eye, and skin.

  7. Clonal selection - Wikipedia

    en.wikipedia.org/wiki/Clonal_selection

    4) inactive lymphocytes. Most of these never encounter a matching 5) foreign antigen, but those that do are activated and produce 6) many clones of themselves. In immunology, clonal selection theory explains the functions of cells of the immune system (lymphocytes) in response to specific antigens invading the body.

  8. Cell-mediated immunity - Wikipedia

    en.wikipedia.org/wiki/Cell-mediated_immunity

    Cellular immunity protects the body through: T-cell mediated immunity or T-cell immunity: activating antigen-specific cytotoxic T cells that are able to induce apoptosis in body cells displaying epitopes of foreign antigen on their surface, such as virus-infected cells, cells with intracellular bacteria, and cancer cells displaying tumor antigens;

  9. B cell - Wikipedia

    en.wikipedia.org/wiki/B_cell

    B cells, also known as B lymphocytes, are a type of white blood cell of the lymphocyte subtype. [1] They function in the humoral immunity component of the adaptive immune system . [ 1 ] B cells produce antibody molecules which may be either secreted or inserted into the plasma membrane where they serve as a part of B-cell receptors . [ 2 ]

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