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  2. Soluble guanylate cyclase stimulator - Wikipedia

    en.wikipedia.org/wiki/Soluble_guanylate_cyclase...

    Soluble guanylate cyclase (sGC) stimulators are a class of drugs developed to treat heart failure, pulmonary hypertension, and other diseases. The first-in-class medication was riociguat, approved in 2013 for pulmonary hypertension. [1] [2] They have also been investigated for hypertension, systemic sclerosis, and sickle cell disease. [3] [1]

  3. Pulmonary hypertension - Wikipedia

    en.wikipedia.org/wiki/Pulmonary_hypertension

    Pulmonary hypertension (PH or PHTN) is a condition of increased blood pressure in the arteries of the lungs. [7] Symptoms include shortness of breath, fainting, tiredness, chest pain, swelling of the legs, and a fast heartbeat. [7] [1] The condition may make it difficult to exercise. [7] Onset is typically gradual. [8]

  4. Antihypertensive - Wikipedia

    en.wikipedia.org/wiki/Antihypertensive

    The choice between the drugs is to a large degree determined by the characteristics of the patient being prescribed for, the drugs' side effects, and cost. Most drugs have other uses; sometimes the presence of other symptoms can warrant the use of one particular antihypertensive. Examples include: Age can affect the choice of medications.

  5. Riociguat - Wikipedia

    en.wikipedia.org/wiki/Riociguat

    Riociguat, sold under the brand name Adempas, is a medication by Bayer that is a stimulator of soluble guanylate cyclase (sGC). It is used to treat two forms of pulmonary hypertension (PH): chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension (PAH).

  6. 'I Have Postcapillary Pulmonary Hypertension. Here's the ...

    www.aol.com/lifestyle/postcapillary-pulmonary...

    The First Postcapillary Pulmonary Hypertension Sign One Woman Noticed In June 2023, Hopkins noticed she had breathing difficulties even with light physical activity. "It came on very quickly ...

  7. Merck's therapy for rare lung condition shown to help reduce ...

    www.aol.com/news/mercks-therapy-rare-lung...

    Merck said its drug met the main goal of significantly reducing the time to disease worsening, lung transplantation or death in a late-stage study of 172 patients with advanced stages of the ...

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