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The Dosage Index is a mathematical figure used by breeders of Thoroughbred race horses, and sometimes by bettors handicapping horse races, to quantify a horse's ability, or inability, to negotiate the various distances at which horse races are run. It is calculated based on an analysis of the horse's pedigree.
The computed tomography dose index (CTDI) is a commonly used radiation exposure index in X-ray computed tomography (CT), first defined in 1981. [1] [2] The unit of CTDI is the gray (Gy) and it can be used in conjunction with patient size to estimate the absorbed dose.
A Dosage Index of under 4.00 is considered optimal for horses attempting to win classic races. [7] As the Dosage Profile and Index are widely published, breeders may select mates for their mare with these figures in mind, especially if they are intending to sell the foal at auction.
For many drugs, severe toxicities in humans occur at sublethal doses, which limit their maximum dose. A higher safety-based therapeutic index is preferable instead of a lower one; an individual would have to take a much higher dose of a drug to reach the lethal threshold than the dose taken to induce the therapeutic effect of the drug.
The median effective dose is the dose that produces a quantal effect (all or nothing) in 50% of the population that takes it (median referring to the 50% population base). [6] It is also sometimes abbreviated as the ED 50, meaning "effective dose for 50% of the population". The ED50 is commonly used as a measure of the reasonable expectancy of ...
Quantitatively, it is the ratio given by the toxic dose divided by the therapeutic dose. A protective index is the toxic dose of a drug for 50% of the population (TD 50) divided by the minimum effective dose for 50% of the population (ED 50). A high protective index is preferable to a low one: this corresponds to a situation in which one would ...
Nearly half of U.S. adults still believe that the benefits of taking low-dose aspirin daily outweighs the risks — despite new guidance that suggests otherwise, according to a new survey. The ...
A dose–response curve is a coordinate graph relating the magnitude of a dose (stimulus) to the response of a biological system. A number of effects (or endpoints) can be studied. The applied dose is generally plotted on the X axis and the response is plotted on the Y axis. In some cases, it is the logarithm of the dose that is plotted on the ...