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2. Doxepin - Wikipedia

   en.wikipedia.org/wiki/Doxepin

   Doxepin is a highly potent antihistamine, with this being its strongest activity. [49] [53] [57] [8] In fact, doxepin has been said to be the most or one of the most potent H 1 receptor antagonists available, with one study finding an in vitro K i of 0.17 nM. [37]

3. Which Allergy Medicine Is Actually Most Effective? - AOL

   www.aol.com/lifestyle/allergy-medicine-actually...

   “While antihistamines [like Zyrtec and Claritin] can help with sneezing, itching and runny nose, first line therapy for relief of nasal congestion includes a steroid or antihistamine nose spray.”

4. Doxepin for Depression, Insomnia & More: Everything You Need ...

   www.aol.com/doxepin-depression-insomnia-more...

   Since it has strong antihistamine properties, topical doxepin, in cream form, treats itching caused by skin conditions like lichen simplex chronicus and atopic dermatitis.

5. H1 antagonist - Wikipedia

   en.wikipedia.org/wiki/H1_antagonist

   H 1-antihistamines can be administered topically (through the skin, nose, or eyes) or systemically, based on the nature of the allergic condition. The authors of the American College of Chest Physicians Updates on Cough Guidelines (2006) recommend that, for cough associated with the common cold, first-generation antihistamine-decongestants are ...

6. Antihistamine - Wikipedia

   en.wikipedia.org/wiki/Antihistamine

   H 1-antihistamines work by binding to histamine H 1 receptors in mast cells, smooth muscle, and endothelium in the body as well as in the tuberomammillary nucleus in the brain. Antihistamines that target the histamine H 1-receptor are used to treat allergic reactions in the nose (e.g., itching, runny nose, and

7. Doxylamine - Wikipedia

   en.wikipedia.org/wiki/Doxylamine

   Doxylamine and other first-generation antihistamines are the most widely used sleep medications in the world. [6] Typical side effects of doxylamine (at recommended doses) include dizziness, drowsiness, grogginess, and dry mouth, among others. [7] [4] As an antihistamine, doxylamine is an inverse agonist of the histamine H 1 receptor.