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In the absence of Graves' ophthalmopathy, patients may demonstrate other ophthalmic symptoms and signs due to hyperthyroidism: Dry eyes (due to loss of corneal moisture). [24] A sense of irritation, discomfort, or pain in the eyes. A tingling sensation behind the eyes or the feeling of grit or sand in the eyes.
Graves disease, also known as toxic diffuse goiter or Basedow’s disease, is an autoimmune disease that affects the thyroid. [1] It frequently results in and is the most common cause of hyperthyroidism. [5] It also often results in an enlarged thyroid. [1] Signs and symptoms of hyperthyroidism may include irritability, muscle weakness ...
0.3–0.4% (USA) [ 8 ] Hypothyroidism (also called underactive thyroid, low thyroid or hypothyreosis) is a disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormones. [ 3 ] It can cause a number of symptoms, such as poor ability to tolerate cold, extreme fatigue, muscle aches, constipation, slow heart ...
Various authors have suggested that thyrotoxic myopathy is a result of the weight loss and generalized asthenia associated with hyperthyroidism. Muscle involvement has been reported to occur in about 80% of thyrotoxic patients (see section #Epidemiology ), [ 7 ] and the most common causes of hyperthyroidism are Graves’ disease , toxic ...
Euthyroid sick syndrome (ESS) is a state of adaptation or dysregulation of thyrotropic feedback control [1] wherein the levels of T3 and/or T4 are abnormal, but the thyroid gland does not appear to be dysfunctional. This condition may result from allostatic responses of hypothalamus-pituitary-thyroid feedback control, dyshomeostatic disorders ...
Thyroxine-binding globulin (TBG) is a globulin protein encoded by the SERPINA7 gene in humans. TBG binds thyroid hormones in circulation. It is one of three transport proteins (along with transthyretin and serum albumin) responsible for carrying the thyroid hormones thyroxine (T 4) and triiodothyronine (T 3) in the bloodstream.
Hypermetabolism is defined as an elevated resting energy expenditure (REE) > 110% of predicted REE. [1] Hypermetabolism is accompanied by a variety of internal and external symptoms, most notably extreme weight loss, and can also be a symptom in itself. This state of increased metabolic activity can signal underlying issues, especially ...
Symptoms of congestive heart failure include: Shortness of breath. Swelling in the legs. Bloating in the abdomen. Fatigue. Heart failure, in general, remains common affecting one in four people in ...
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