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The laboratory mouse or lab mouse is a small mammal of the order Rodentia which is bred and used for scientific research or feeders for certain pets. Laboratory mice are usually of the species Mus musculus. They are the most commonly used mammalian research model and are used for research in genetics, physiology, psychology, medicine and other ...
Laboratory rats or lab rats are strains of the rat subspecies Rattus norvegicus domestica (Domestic Norwegian rat) which are bred and kept for scientific research. While less commonly used for research than laboratory mice , rats have served as an important animal model for research in psychology and biomedical science .
Many laboratory animals, including mice and rats, are chronically stressed which can also negatively affect research outcomes and the ability to accurately extrapolate findings to humans. [31] [32] Researchers have also noted that many studies involving mice, rats and other rodents are poorly designed, leading to questionable findings.
The house mouse is best identified by the sharp notch in its upper front teeth. House mice have an adult body length (nose to base of tail) of 7.5–10 centimetres (3–4 in) and a tail length of 5–10 cm (2–4 in). The weight is typically 11–30 g (8 –1 oz). In the wild they vary in color from grey and light brown to black (individual ...
In the U.S., the numbers of rats and mice used is estimated to be from 11 million [94] to between 20 and 100 million a year. [95] Other rodents commonly used are guinea pigs, hamsters, and gerbils. Mice are the most commonly used vertebrate species because of their size, low cost, ease of handling, and fast reproduction rate.
The Animal Welfare Act (Laboratory Animal Welfare Act of 1966, Pub. L. 89–544) was signed into law by President Lyndon B. Johnson on August 24, 1966. [1] It is the main federal law in the United States that regulates the treatment of animals in research and exhibition. Other laws, policies, and guidelines may include additional species ...
Followed by. Racso and the Rats of NIMH. Mrs. Frisby and the Rats of NIMH is a 1971 children's science fiction/fantasy book by Robert C. O'Brien, with illustrations by Zena Bernstein. The novel was published by the Los Angeles publishing house Atheneum Books. This book was the winner of numerous awards including the 1972 Newbery Medal. [3]
BALB/c is an albino, laboratory-bred strain of the house mouse from which a number of common substrains are derived. Now over 200 generations from New York in 1920, BALB/c mice are distributed globally, and are among the most widely used inbred strains used in animal experimentation.
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