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Dementia with Lewy bodies (DLB) is a type of dementia, a group of diseases involving progressive neurodegeneration of the central nervous system. [11] It is one of the two Lewy body dementias, along with Parkinson's disease dementia.
Johnson lists vascular dementia, Lewy Body dementia, frontotemporal dementia and a rare primarily visual dementia called posterior cortical atrophy as examples. ... Other Early Signs of Dementia.
[12] [13] The Lewy body dementias—dementia with Lewy bodies (DLB), and Parkinson's disease dementia (PDD)—are distinguished by the timing when cognitive and motor symptoms appear. [14] The two Lewy body dementias are often considered to belong on a spectrum of Lewy body disease that includes Parkinson's disease. [2] [5]
Pre-dementia or early-stage dementia (stages 1, 2, and 3). ... doctors and caregivers will likely observe hallmark signs that dementia is getting worse, including difficulties with language and ...
When picturing signs of dementia to look for, the first ones that come to mind may be memory loss, ... Related: The Unexpected Early Dementia Sign You Might Miss, According to Neurologists.
The DNA repair function of alpha-synuclein appears to be compromised in Lewy body inclusion bearing neurons, and this may trigger cell death. Study of synucleinopathy mouse models of Parkinson's disease indicates that alpha-synuclein pathogenesis is associated with increased DNA damage and activation of the DNA damage response.
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