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Pregnenolone (P5), or pregn-5-en-3β-ol-20-one, is an endogenous steroid and precursor/metabolic intermediate in the biosynthesis of most of the steroid hormones, including the progestogens, androgens, estrogens, glucocorticoids, and mineralocorticoids. [1]
Pregnenolone, sold under the brand name Enelone among others, is a medication and supplement as well as a naturally occurring and endogenous steroid. [3] [1] [4] [5] [6] It is described as a neurosteroid and anti-inflammatory drug and was used in the treatment of rheumatoid arthritis and soft-tissue rheumatism in the 1950s and is no longer prescribed today, but remains available as a supplement.
Pregnanolone was investigated for clinical use as a general anesthetic under the name eltanolone (INN Tooltip International Nonproprietary Name), but produced unwanted side effects such as convulsions on occasion, and for this reason, was never marketed.
In addition to the lack of research showing the benefits of testosterone for women, taking the hormone can also come with side effects, including unwanted hair growth, acne, liver damage, hair ...
Side effects of ethisterone include masculinization among others. [4] [7] [8] Ethisterone is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. [9] It has some androgenic and anabolic activity and no other important hormonal activity. [9] [10 ...
[2] [3] It has been reported to reduce wrinkles in elderly women when applied in the form of a 0.5% topical cream, effects which were suggested to be due to improved hydration of the skin. [3] Pregnenolone acetate has been marketed in France in a topical cream containing 1% pregnenolone acetate and 10% " sex hormone " for the treatment of ...
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