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Nausea and vomiting; Sedation (first-generation H 1-antihistamines) H 1-antihistamines can be administered topically (through the skin, nose, or eyes) or systemically, based on the nature of the allergic condition.
Hydroxyzine, sold under the brand names Atarax and Vistaril among others, is an antihistamine medication. [8] It is used in the treatment of itchiness, anxiety, insomnia, and nausea (including that due to motion sickness). [8]
Diphenhydramine, sold under the brand name Benadryl among others, is an antihistamine and sedative. It is a first-generation H 1-antihistamine and it works by blocking certain effects of histamine, which produces its antihistamine and sedative effects. [11] [2] Diphenhydramine is also a potent anticholinergic. [12]
Dimenhydrinate, also known by the brand name Dramamine, is a popular option to help reduce motion sickness symptoms like nausea. However, it is an antihistamine, which means it may cause ...
Cinnarizine is an antihistamine and calcium channel blocker of the diphenylmethylpiperazine group. [5] It is prescribed for nausea and vomiting due to motion sickness [6] or other sources such as chemotherapy, [7] vertigo, [8] or Ménière's disease. [9] Cinnarizine is one of the leading causes of drug-induced parkinsonism. [5]
Thankfully, though, there are several remedies for motion sickness, from prescribed patches to over-the-counter antihistamines. ... To help reduce nausea, you can also try ginger chews or lozenges ...
Some antihistamines have a calming effect, making them an effective option for mild to moderate anxiety. They can also help to promote sleep — a common difficulty for people with anxiety.
Antihistamines (H 1 histamine receptor antagonists) are effective in many conditions, including motion sickness, morning sickness in pregnancy, and to combat opioid nausea. H1 receptors in central areas include area postrema and vomiting center in the vestibular nucleus.
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