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Euphoria (/ juː ˈ f ɔːr i ə / ⓘ yoo-FOR-ee-ə) is the experience (or affect) of pleasure or excitement and intense feelings of well-being and happiness. [1] [2] Certain natural rewards and social activities, such as aerobic exercise, laughter, listening to or making music and dancing, can induce a state of euphoria.
Activation of the μ-opioid receptor by an agonist such as morphine causes analgesia, sedation, slightly reduced blood pressure, itching, nausea, euphoria, decreased respiration, miosis (constricted pupils), and decreased bowel motility often leading to constipation. Some of these effects, such as analgesia, sedation, euphoria, itching and ...
The euphoria, comprehensive alleviation of distress and therefore all aspects of suffering, promotion of sociability and empathy, "body high", and anxiolysis provided by narcotic drugs including opioids can cause the use of high doses in the absence of pain for a protracted period, which can impart a craving for the drug in the user. [156]
The improvement and deterioration of mood (euphoria and dysphoria) are represented in the cognitive schema as high and low elevations; thus, after the drug has elevated the mood (a state known as a high), there follows a period of coming back down, which often has a distinct character from withdrawal in stimulants.
Knowing what situations, places, things, or people may be associated with either euphoria or dysphoria can help you make healthier lifestyle choices. Pattarisara Suvichanarakul / iStock Get Help ...
The evolutionary role of opioid signaling in these behaviors was confirmed in dogs, chicks, and rats. [18] Opioid receptors also have a role in mating behaviors. [20] However, mu-opioid receptors do not just control social behavior because they also make individuals feel relaxed in a wide range of other situations. [citation needed]
The opioid epidemic took hold in the U.S. in the 1990s. Percocet, OxyContin and Opana became commonplace wherever chronic pain met a chronic lack of access to quality health care, especially in Appalachia. The Centers for Disease Control and Prevention calls the prescription opioid epidemic the worst of its kind in U.S. history.
Buprenorphine's activity as an agonist/antagonist is important in the treatment of opioid use disorder: it relieves withdrawal symptoms from other opioids and induces some euphoria, but also blocks the ability for many other opioids, including heroin, to cause an effect.