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ERPF = 540 mL/min Effective renal plasma flow (eRPF) is a measure used in renal physiology [ 1 ] to calculate renal plasma flow (RPF) and hence estimate renal function . Because the extraction ratio of PAH is high, it has become commonplace to estimate the RPF by dividing the amount of PAH in the urine by the plasma PAH level, ignoring the ...
Para-aminohippurate (PAH) clearance is a method used in renal physiology to measure renal plasma flow, which is a measure of renal function. [citation needed]PAH is completely removed from blood that passes through the kidneys (PAH undergoes both glomerular filtration and tubular secretion), and therefore the rate at which the kidneys can clear PAH from the blood reflects total renal plasma flow.
U In = 150 mg/mL U Cr = 1.25 mg/mL U PAH = C Na = 5 mL/min C In = 150 mL/min C Cr = 125 mL/min C PAH = 420 mL/min ER = 90% ERPF = 540 mL/min
Extraction ratio is a measure in renal physiology, primarily used to calculate renal plasma flow in order to evaluate renal function. It measures the percentage of the compound entering the kidney that was excreted into the final urine. [1] Measured in concentration in blood plasma, it may thus be expressed as:
The combination of 10 mg estradiol enantate and 150 mg DHPA as a once-monthly combined injectable contraceptive (which achieves levels of estradiol of around 350 pg/mL) [10] [43] [44] has been found to have little to no effect on many markers of estrogen-modulated liver protein synthesis, including circulating levels of HDL and LDL cholesterol ...
If one removes 1440 mg in 24 h, this is equivalent to removing 1 mg/min. If the blood concentration is 0.01 mg/mL (1 mg/dL), then one can say that 100 mL/min of blood is being "cleared" of creatinine, since, to get 1 mg of creatinine, 100 mL of blood containing 0.01 mg/mL would need to have been cleared.
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K is the clearance [mL/min] or [m 3 /s] C is the concentration [mmol/L] or [mol/m 3] (in the United States often [mg/mL]) From the above definitions it follows that is the first derivative of concentration with respect to time, i.e. the change in concentration with time. It is derived from a mass balance.