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  2. Chronic lymphocytic leukemia - Wikipedia

    en.wikipedia.org/wiki/Chronic_lymphocytic_leukemia

    Because of the prolonged survival, which was typically about 10 years in past decades, but which can extend to a normal life expectancy, [2] the prevalence (number of people living with the disease) is much higher than the incidence (new diagnoses). CLL is the most common type of leukemia in the UK, accounting for 38% of all leukemia cases.

  3. p53 - Wikipedia

    en.wikipedia.org/wiki/P53

    The TP53 gene is the most frequently mutated gene (>50%) in human cancer, indicating that the TP53 gene plays a crucial role in preventing cancer formation. [5] TP53 gene encodes proteins that bind to DNA and regulate gene expression to prevent mutations of the genome. [12]

  4. Richter's transformation - Wikipedia

    en.wikipedia.org/wiki/Richter's_transformation

    CLL/SLL is the most common adult leukemia in Western countries, accounting for 1.2% of the new cancers diagnosed each year in the United States. It usually occurs in older adults (median age at diagnosis 70) and follows an indolent course over many years. [11] About 1-10% of CLL/SLLs develop a Richter's transformation at a rate of 0.5–1% per ...

  5. Monoclonal B-cell lymphocytosis - Wikipedia

    en.wikipedia.org/wiki/Monoclonal_B-cell_lymphocy...

    Chromosome abnormalities, single nucleotide polymorphisms (SNPs, i.e. substitutions of a single nucleotide in a DNA sequence at a specific position in the genome) and gene mutations, while each occurs in <15% of cases, [12] are present in CLL/SLL MBL and to some extent are similar to those found in CLL/SLL. For example, position 21.33 to 22.2 ...

  6. Why norovirus is so hard to kill: Here's how to protect ... - AOL

    www.aol.com/why-norovirus-hard-kill-heres...

    Even if you have had norovirus before, you can still be infected every year, because there are many different types of the bug, owing to the rapid mutation rate seen in RNA viruses like norovirus.

  7. Chromothripsis - Wikipedia

    en.wikipedia.org/wiki/Chromothripsis

    TP53 mutations have also been expressed in cells that exhibit shorter [clarification needed] and are more end-end fusion prone. It is also hypothesized that TP53 mutations may be implicated in premature chromosome condensation. TP53 may also contribute to the ability of cells to survive the catastrophic event that normally would be considered ...

  8. Travel Worry-Free with These Innovative Automatic Pet Feeders

    www.aol.com/travel-worry-free-innovative...

    A friend referred to her toddlers as anchors: cute, squishy anchors, but anchors nonetheless. The same could be said of our pets — furry, feathered, and finned.

  9. If you’re finding your teenage dog difficult, here’s what an ...

    www.aol.com/finding-teenage-dog-difficult-award...

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