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  2. Trilostane - Wikipedia

    en.wikipedia.org/wiki/Trilostane

    Steroidogenesis.Trilostane inhibits 3β-HSD. Trilostane is a steroidogenesis inhibitor. [1] It is specifically an inhibitor of 3β-hydroxysteroid dehydrogenase (3β-HSD). [1] [15] As a result of this action, trilostane blocks the conversion of Δ 5-3β-hydroxysteroids, including pregnenolone, 17α-hydroxypregnenolone, dehydroepiandrosterone (DHEA), and androstenediol, into Δ 4-3-ketosteroids ...

  3. 3β-Hydroxysteroid dehydrogenase - Wikipedia

    en.wikipedia.org/wiki/3β-hydroxysteroid...

    3β-Hydroxysteroid dehydrogenase/Δ 5-4 isomerase (3β-HSD) (EC 1.1.1.145) is an enzyme that catalyzes the biosynthesis of the steroid progesterone from pregnenolone, 17α-hydroxyprogesterone from 17α-hydroxypregnenolone, and androstenedione from dehydroepiandrosterone (DHEA) in the adrenal gland.

  4. Triamcinolone acetonide - Wikipedia

    en.wikipedia.org/wiki/Triamcinolone_acetonide

    Triamcinolone acetonide, sold under the brand name Kenalog among others, is a synthetic corticosteroid medication used topically to treat various skin conditions, [13] to relieve the discomfort of mouth sores, and by injection into joints to treat various joint conditions.

  5. Cushing's syndrome (veterinary) - Wikipedia

    en.wikipedia.org/wiki/Cushing's_syndrome...

    Trilostane, sold under the brand name Vetoryl, inhibits the 3-beta-hydroxysteroid dehydrogenase enzyme. The enzyme is responsible for the production of cortisol and the inhibition of it will inhibit cortisol production. Trilostane has been identified by multiple studies as an effective treatment for Cushing's.

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  7. Triamcinolone - Wikipedia

    en.wikipedia.org/wiki/Triamcinolone

    Triamcinolone is used to treat many different medical conditions, such as eczema, alopecia areata, lichen sclerosus, psoriasis, arthritis, allergies, ulcerative colitis, lupus, sympathetic ophthalmia, temporal arteritis, uveitis, ocular inflammation, keloids, urushiol-induced contact dermatitis, aphthous ulcers (usually as triamcinolone acetonide), central retinal vein occlusion, visualization ...

  8. 11β-Hydroxysteroid dehydrogenase type 1 - Wikipedia

    en.wikipedia.org/wiki/11β-Hydroxysteroid...

    The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone.In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol.

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