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While 3-methylfentanyl is considerably more potent than fentanyl itself, lofentanil is only slightly stronger than carfentanil. [ 1 ] [ 2 ] This suggests that substitution at both the 3 and 4 positions of the piperidine ring introduces steric hindrance which prevents μ-opioid affinity from increasing much further.
This is a list of cocaine analogues.A cocaine analogue is an (usually) artificial construct of a novel chemical compound from (often the starting point of natural) cocaine's molecular structure, with the result product sufficiently similar to cocaine to display similarity in, but alteration to, its chemical function.
Poppers (or popper) is a slang term referring to recreational drugs belonging to the alkyl nitrite family of chemical compounds. When fumes from these substances are inhaled , they act as potent vasodilators , producing mild euphoria, warmth, and dizziness.
A drug combination chart designed for harm reduction by TripSit [1]. Polysubstance use or multisubstance use is the use of combinations of psychoactive substances with both legal and illegal substances.
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Acetylfentanyl (acetyl fentanyl) is an opioid analgesic drug that is an analog of fentanyl. [4] Studies have estimated acetylfentanyl to be 15 times more potent than morphine, [5] [6] which would mean that despite being somewhat weaker than fentanyl, it is nevertheless still several times stronger than pure heroin.
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