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Quinine has not been shown to reduce the duration (length) of a muscle cramp. [6] Quinine treatment may lead to hematologic and cardiac toxicity. Due to its low effectiveness and negative side effects, its use as a medication for treating muscle cramps is not recommended by the FDA. [26] Magnesium is commonly used to treat muscle cramps.
Cramp fasciculation syndrome (CFS) is a rare [1] peripheral nerve hyperexcitability disorder. It is more severe than the related (and common) disorder known as benign fasciculation syndrome ; it causes fasciculations , cramps, pain, fatigue, and muscle stiffness similar to those seen in neuromyotonia (another related condition). [ 2 ]
Muscle cramps could also potentially stem from a nerve problem (such as nerve compression), exercising in the heat, a lack of stretching, muscle fatigue, body stress, medication side effects or ...
Muscle stiffness may also be present; if muscle weakness is not also present, and cramps are more severe, the stiffness may be categorized instead as cramp fasciculation syndrome. [3] Cramp fasciculation is a variant of BFS which presents with muscle pain and exercise intolerance. [2] [4]
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