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Methylene blue has been described as "the first fully synthetic drug used in medicine." Methylene blue was first prepared in 1876 by German chemist Heinrich Caro. [69] Its use in the treatment of malaria was pioneered by Paul Guttmann and Paul Ehrlich in 1891. During this period before the first World War, researchers like Ehrlich believed that ...
Treatment is generally with oxygen therapy and methylene blue. [3] Other treatments may include vitamin C, exchange transfusion, and hyperbaric oxygen therapy. [3] Outcomes are generally good with treatment. [3] Methemoglobinemia is relatively uncommon, with most cases being acquired rather than genetic. [3]
New methylene blue (also NMB) [clarify] is an organic compound of the thiazine class of heterocycles. It is used as a stain and as an antimicrobial agent. It is classified as an azine dye, and the chromophore is a cation, the anion is often unspecified.
The synthetic dye methylene blue, containing the structure, was described in 1876. Many water-soluble phenothiazine derivatives, such as methylene blue, methylene green, thionine, and others, can be electropolymerized into conductive polymers used as electrocatalysts for NADH oxidation in enzymatic biosensors and biofuel cells. [10] [11] [12]
Wright's stain is a hematologic stain that facilitates the differentiation of blood cell types. It is classically a mixture of eosin (red) and methylene blue dyes. It is used primarily to stain peripheral blood smears, urine samples, and bone marrow aspirates, which are examined under a light microscope.
Marburg is a rare but “severe hemorrhagic fever that can cause serious illness and death,” the U.S. Centers for Disease Control says, adding that there is no treatment or vaccine for it.
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