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Many patients will not develop these side effects, although there is still a significant possibility of risks associated with Antipsychotic usage. The percentage of patients affected by side effects like Tardive dyskinesia is significantly high and estimated to be a 20-50% prevalence. [1] [2]
Common side effects include sedation, fatigue, weight gain, constipation, and dry mouth. [11] Other side effects include low blood pressure with standing, seizures, a prolonged erection, high blood sugar, tardive dyskinesia, and neuroleptic malignant syndrome. [11] In older people with dementia, its use increases the risk of death. [11]
[4] [3] Although atypical antipsychotics are thought to be safer than typical antipsychotics, they still have severe side effects, including tardive dyskinesia (a serious movement disorder), neuroleptic malignant syndrome, and increased risk of stroke, sudden cardiac death, blood clots, and diabetes. Significant weight gain may occur. Critics ...
Some side effects, such as weight gain, occur more frequently with certain types of antidepressant medication. Switching to a new type of antidepressant may help reverse any weight gain you’ve ...
Some atypicals are associated with considerable weight gain, diabetes and the risk of metabolic syndrome. [110] Unwanted side effects cause people to stop treatment, resulting in relapses. [111] Risperidone (atypical) has a similar rate of extrapyramidal symptoms to haloperidol (typical). [110]
In humans the effects of excess serotonin were first noted in 1960 in patients receiving an MAOI and tryptophan. [54] The syndrome is caused by increased serotonin in the CNS. [6] It was originally suspected that agonism of 5-HT 1A receptors in central grey nuclei and the medulla oblongata was responsible for the development of the syndrome. [55]
Asenapine and quetiapine may have interactions with medications having similar side effects, such as sedation, anticholinergic effects, weight gain, hypotension or Parkinsonism, which may cause more serious side effects.
Adverse effects that threaten serious harm, aggravate other medical conditions, or make a person want to stop taking their medications are all examples of drug intolerance. Certain drug interactions can cause adverse effects as well. [1] Patient/guardian preference: A patient or caregiver may prefer a different antipsychotic. This may be due to ...