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Advantages include reduced side effects and reduced risk of the bacterium developing resistance, since [5] bacteriophages are much more specific than antibiotics. They are typically harmless not only to the host organism but also to other beneficial bacteria, such as the gut microbiota , reducing the chances of opportunistic infections . [ 6 ]
Many of these effects are probably indirect, hence the challenge becomes to identify the direct interactions among bacteria and phage. [80] Several attempts have been made to map protein–protein interactions among phage and their host. For instance, bacteriophage lambda was found to interact with its host, E. coli, by dozens of interactions ...
Some of the most popular drugs prescribed to treat bacterial infections can cause serious side effects and are overprescribed, according to studies and reports.
Some drugs need to be used with caution in patients with renal dysfunction. The use of nitrofurantoin is contraindicated in patients with an estimated GFR of less than 30 mL/min/1.73m 2 as drug accumulation can lead to increased side effects and impaired recovery of the urinary tract, increasing the risk of treatment failure. [29]
Two separate patients who were prescribed a popular class of antibiotic told WFTS the drug came with severe side effects. For both women, the family of antibiotics known as fluoroquinolones ...
After D-Day, the new antibiotic drug penicillin became public knowledge and found its way into the hospitals in the west. As it was more reliable and easier to use than phage therapy, it soon became the method of choice, despite side effects and problems with resistant bacteria.
Mycobacteriophage Bxb1 Structure [1]. A mycobacteriophage is a member of a group of bacteriophages known to have mycobacteria as host bacterial species. While originally isolated from the bacterial species Mycobacterium smegmatis and Mycobacterium tuberculosis, [2] the causative agent of tuberculosis, more than 4,200 mycobacteriophage species have since been isolated from various environmental ...
Interactions between alcohol and certain antibiotics may occur and may cause side effects and decreased effectiveness of antibiotic therapy. [60] [61] While moderate alcohol consumption is unlikely to interfere with many common antibiotics, there are specific types of antibiotics with which alcohol consumption may cause serious side effects. [62]