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Two-component systems accomplish signal transduction through the phosphorylation of a response regulator (RR) by a histidine kinase (HK). Histidine kinases are typically homodimeric transmembrane proteins containing a histidine phosphotransfer domain and an ATP binding domain, though there are reported examples of histidine kinases in the atypical HWE and HisKA2 families that are not ...
In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating gene activity. A single gene can be regulated in a range of ways, from altering the number of copies of RNA that are transcribed, to the temporal control of when the gene is ...
Dual control theory is a branch of control theory that deals with the control of systems whose characteristics are initially unknown. [1] [2] It is called dual because in controlling such a system the controller's objectives are twofold: (1) Action: To control the system as well as possible based on current system knowledge
Dual inheritance theory (DIT), also known as gene–culture coevolution or biocultural evolution, [1] was developed in the 1960s through early 1980s to explain how human behavior is a product of two different and interacting evolutionary processes: genetic evolution and cultural evolution.
This interaction promotes and enhances the TCR signaling, but can also be bi-directional. [2] The co-stimulatory signal is necessary for T cell proliferation, differentiation and survival. Activation of T cells without co-stimulation may lead to the unresponsiveness of the T cell (also called anergy ), apoptosis or the acquisition of the immune ...
One of the best post-Christmas sales we look forward to every year is Nordstrom's Half-Yearly Sale, which typically kicks off the day after Christmas and lasts for a couple of weeks.Ring in the ...
South Africa beat Sri Lanka by 109 runs on the last morning of the second cricket test at St George's Park and swept the series 2-0 on Monday. The odds favored South Africa, which needed five more ...
In evolutionary biology, an evolutionary tradeoff is a situation in which evolution cannot advance one part of a biological system without distressing another part of it. In this context, tradeoffs refer to the process through which a trait increases in fitness at the expense of decreased fitness in another trait.