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Syrup of ipecac (/ ˈ ɪ p ɪ k æ k /), or simply ipecac, is a drug that was once widely used as an expectorant (in low doses) and a rapid-acting emetic (in higher doses). It is obtained from the dried rhizome and roots of the ipecacuanha plant ( Carapichea ipecacuanha ), from which it derives its name.
Ipecac plant. Carapichea ipecacuanha is a species of flowering plant in the family Rubiaceae.It is native to Costa Rica, Nicaragua, Panama, Colombia, and Brazil. Its common name, ipecacuanha (Portuguese pronunciation: [ipekɐkuˈɐ̃ɲɐ]), is derived from the Tupi ypekakûãîa (lit.
Developed in 1732 by English physician Thomas Dover, [1] the powder was an old preparation of powder of ipecacuanha (which was formerly used to produce syrup of ipecac), opium in powder, and potassium sulfate. Initially designed to treat gout, it was later recommended for general pains, insomnia, and diarrhea, among others.
It describes that Dr. Rush's cure for the fever, along with bleeding, was a mix of herbs and chemicals used to purge the body of all its contents. It would enduce vimiting and diarrea to do so, just as ipecac syrup enduces vomitting. "Ipecac (not syrup of ipecac) is also used as a homeopathic remedy for nausea.
Paregoric was a household remedy in the 18th and 19th centuries when it was widely used to control diarrhea in adults and children, as an expectorant and cough medicine, to calm fretful children, and to rub on the gums to counteract the pain from teething. A formula for paregoric from Dr. Chase's Recipes (1865): [7]
"rare and mild gastrointestinal upset, headaches, diarrhea, gynecomastia, paroxysmal atrial fibrillation, ventricular rupture and death in one patient" [3] Senna: Egyptian senna Senna alexandrina (Cassia senna) "abdominal pain, diarrhea, potentially carcinogenic, with others can potentiate cardiac glycosides and antiarrhythmic agents", [3 ...
Chronic diarrhea (alternate spelling: diarrhoea) of infancy, also called toddler's diarrhea, is a common condition typically affecting up to 1.7 billion children between ages 6–30 months worldwide every year, usually resolving by age 4.
Guaifenesin might act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi via stimulation of the gastric mucosa. . This stimulation leads to an increased parasympathetic activity in the respiratory tract via the so-called gastro-pulmonary reflex, although some in vitro studies suggested that it might also act directly on the ...
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