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The genus Thymus (/ ˈ t aɪ m ə s / TY-məs; [3] thymes) contains about 350 [4] species of aromatic perennial herbaceous plants and subshrubs in the family Lamiaceae. It is native to the Old World. It is native to the Old World.
The thymus is present in all jawed vertebrates, where it undergoes the same shrinkage with age and plays the same immunological function as in other vertebrates. Recently, in 2011, a discrete thymus-like lympho-epithelial structure, termed the thymoid , was discovered in the gills of larval lampreys . [ 37 ]
Thymus vulgaris (common thyme, German thyme, [1] garden thyme [2] or just thyme) is a species of flowering plant in the mint family Lamiaceae, native to southern Europe from the western Mediterranean to southern Italy.
TECs, as a component of the thymus, play a key role in thymocyte development and self-tolerance, so their dysfunction causes many autoimmune diseases, tumors of immunodeficiencies. Most frequently are occurred epithelial tumors established from TEC and thymocytes - thymomas and thymic carcinoma .
The chemical composition of Thymus (thyme) includes a variety of essential oils, flavonoids, phenolic acids, triterpenes, and other compounds. The essential oils found in thyme include thymol, which is a major component responsible for the plant's antiseptic properties, and carvacrol, another primary component with similar functions. Other ...
Major function of cTECs is to positively select those T cells that are capable to recognize and interact with MHC molecules on their surface [3]. Once T cell precursors enter the thymic cortex, they start their transformation from double negative stages (T cell without surface expression of CD4 and CD8 co-receptors) to a double positive stage (T cell with surface expression of both co ...
Thymus stromal cells are subsets of specialized cells located in different areas of the thymus. [1] They include all non-T-lineage cells, such as thymic epithelial cells (TECs), endothelial cells, mesenchymal cells, dendritic cells, and B lymphocytes, and provide signals essential for thymocyte development and the homeostasis of the thymic stroma.
The thymus is where the T lymphocytes mature and become immunocompetent. The loss or lack of the thymus results in severe immunodeficiency and subsequent high susceptibility to infection. In most species, the thymus consists of lobules divided by septa which are made up of epithelium which is often considered an epithelial organ.