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Other causes include vasculitis and in situ thrombosis related to hypercoagulable states. [53] Additional mechanisms of peripheral artery disease include arterial spasm and fibromuscular dysplasia. [19] The cause and pathophysiology of arterial spasm are not fully understood, but it is hypothesised that they can occur secondary to trauma. [54]
The most common cause of CVI is superficial venous reflux which is a treatable condition. [2] As functional venous valves are required to provide for efficient blood return from the lower extremities, this condition typically affects the legs.
Causes [2] of venous stasis include: Obesity; Pregnancy; Previous damage to leg; Blood clot; Smoking; Swelling and inflammation of a vein close to the skin; Congestive heart failure. [3] Long periods of immobility that can be encountered from driving, [4] flying, bed rest/hospitalization, or having an orthopedic cast.
The lower legs and the forearms are the most frequent sites affected by compartment syndrome. Other areas of the body such as thigh, buttock, hand, abdomen, and foot can also be affected. [19] [14] The most common cause of acute compartment syndrome is fracture of a bone, most commonly the tibia. [29]
poor leg circulation because of peripheral arterial disease. aortic stenosis, a narrowing of the valve between the heart’s lower left chamber and the aorta ... Those LDL-lowering treatments ...
At times, DVT can cause symptoms in both arms or both legs, as with bilateral DVT. [25] Rarely, a clot in the inferior vena cava can cause both legs to swell. [26] Superficial vein thrombosis, also known as superficial thrombophlebitis, is the formation of a blood clot (thrombus) in a vein close to the skin.
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