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If the impaired vein function causes significant symptoms, such as swelling and ulcer formation, it is referred to as chronic venous disease. [3] It is sometimes called chronic peripheral venous insufficiency and should not be confused with post-thrombotic syndrome in which the deep veins have been damaged by previous deep vein thrombosis .
Other causes include vasculitis and in situ thrombosis related to hypercoagulable states. [53] Additional mechanisms of peripheral artery disease include arterial spasm and fibromuscular dysplasia. [19] The cause and pathophysiology of arterial spasm are not fully understood, but it is hypothesised that they can occur secondary to trauma. [54]
Rest pain is a continuous burning pain of the lower leg or feet. It begins, or is aggravated, after reclining or elevating the limb and is relieved by sitting or standing. It is more severe than intermittent claudication, which is also a pain in the legs from arterial insufficiency. [citation needed]
Acute limb ischemia may also be caused by traumatic disruption of blood flow to a limb, which may present with either hard signs or soft signs of vascular injury. [15] Hard signs include pulsatile bleeding, expanding hematomas (collections of blood), or absent distal pulses, and must be taken to surgery emergently.
Symptoms classically affect a leg and typically develop over hours or days, [20] though they can develop suddenly or over a matter of weeks. [21] The legs are primarily affected, with 4–10% of DVT occurring in the arms. [11] Despite the signs and symptoms being highly variable, [5] the typical symptoms are pain, swelling, and redness.
A poor diet also raises your risk of obesity, making the heart work harder to pump blood throughout the body. Lack of exercise. Physical inactivity is the fourth leading risk factor of death ...
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