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A large number of hierarchies of evidence have been proposed. Similar protocols for evaluation of research quality are still in development. So far, the available protocols pay relatively little attention to whether outcome research is relevant to efficacy (the outcome of a treatment performed under ideal conditions) or to effectiveness (the outcome of the treatment performed under ordinary ...
Homoploid means "at the same ploidy level", i.e. having the same number of homologous chromosomes. For example, homoploid hybridization is hybridization where the offspring have the same ploidy level as the two parental species. This contrasts with a common situation in plants where chromosome doubling accompanies or occurs soon after ...
An important use of MLPA is to determine relative ploidy. For example, probes may be designed to target various regions of chromosome 21 of a human cell. The signal strengths of the probes are compared with those obtained from a reference DNA sample known to have two copies of the chromosome.
The list of organisms by chromosome count describes ploidy or numbers of chromosomes in the cells of various plants, animals, protists, and other living organisms.This number, along with the visual appearance of the chromosome, is known as the karyotype, [1] [2] [3] and can be found by looking at the chromosomes through a microscope.
Scientific evidence is evidence that serves to either support or counter a scientific theory or hypothesis, [1] although scientists also use evidence in other ways, such as when applying theories to practical problems. [2] Such evidence is expected to be empirical evidence and interpretable in accordance with the scientific method.
Furthermore, there is strong evidence that the average statistical power of a study in many scientific fields is well below the benchmark level of 0.8. [ 2 ] [ 3 ] [ 4 ] Given the realities of bias, low statistical power, and a small number of true hypotheses, Ioannidis concludes that the majority of studies in a variety of scientific fields ...
The X-chromosome is also a form of nuclear DNA. Since it is found as 1 copy in males and 2 non-identical chromosomes in females it has a ploidy of 1.5. However, in humans the effective ploidy is somewhat higher, ~1.7, as females in the breeding population have tended to outnumber males by 2:1 during a large portion of human prehistory.
Comparative genomic hybridization (CGH) is a molecular cytogenetic method for analysing copy number variations (CNVs) relative to ploidy level in the DNA of a test sample compared to a reference sample, without the need for culturing cells.