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Alpha-fetoprotein (AFP, α-fetoprotein; ... The normal range of AFP for adults and children is variously reported as under 50, under 10, or under 5 ng/mL.
Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...
In adults a normal amount of AFP is 0-40nng/mL and high levels of this can indicate diseases, cancer, and fetal defects. In pregnant people AFP levels rise at 14 weeks until 32 weeks, and range between 10 and 150 ng/mL in the middle of gestation. This is why AFP can be used alongside other tests as a tumor marker protein in adults. [12]
Elevated alpha-fetoprotein refers to a state where alpha-fetoprotein levels are outside of the reference range. There are two categories of AFP tests: tests performed on serum (blood plasma), and tests performed on amniotic fluid. Tests performed on serum are further categorized by the reason for performing the test: maternal serum, adult tumor ...
normal range 2-62 × 10 −9: chronic poisoning ... alpha-1-Fetoprotein: ... adult, range 4.3-11.0 × 10 6: total, adult, median ...
Alpha-fetoprotein (AFP) is significantly expressed in foetal liver. However, the mechanism that led to the suppression of AFP synthesis in adults is not fully known. Exposure of the liver to cancer-causing agents and arrest of liver maturation in childhood can lead to the rise in AFP. AFP can reach until 400–500 μg/L in hepatocellular ...
The most common method of testing for hepatoblastoma is a blood test checking the alpha-fetoprotein level. Alpha-fetoprotein (AFP) is used as a biomarker to help determine the presence of liver cancer in children. At birth, infants have relatively high levels of AFP, which fall to normal adult levels by the second year of life. The normal level ...
As an example, Alpha-fetoprotein (AFP) testing is used to screen for a neural tube defect (NTD) during the second trimester of pregnancy. If the median AFP result at 16 weeks of gestation is 30 ng/mL and a pregnant woman's AFP result at that same gestational age is 60 ng/mL, then her MoM is equal to 60/30 = 2.0.