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  2. Tamoxifen - Wikipedia

    en.wikipedia.org/wiki/Tamoxifen

    Tamoxifen, sold under the brand name Nolvadex among others, is a selective estrogen receptor modulator used to prevent breast cancer in women and men. [13] It is also being studied for other types of cancer. [13] It has been used for Albright syndrome. [14] Tamoxifen is typically taken daily by mouth for five years for breast cancer. [14]

  3. Selective estrogen receptor modulator - Wikipedia

    en.wikipedia.org/wiki/Selective_estrogen...

    Tamoxifen is a pure antiestrogenic trans-isomer and has differential actions at estrogen target tissues throughout the body. Tamoxifen is selectively antiestrogenic in the breast but estrogen-like in bones and endometrial cancer. [24] Tamoxifen undergo phase I metabolism in the liver by microsomal cytochrome P450 (CYP) enzymes.

  4. Study of Tamoxifen and Raloxifene - Wikipedia

    en.wikipedia.org/wiki/Study_of_Tamoxifen_and...

    The Study of Tamoxifen and Raloxifene (STAR) is a clinical trial from the early 2000s designed determine how the drug raloxifene compares with the drug tamoxifen in reducing the incidence of breast cancer in women who are at increased risk of the disease.

  5. What is stage I triple-positive breast cancer? - AOL

    www.aol.com/lifestyle/office-star-jenna-fischer...

    But most people diagnosed with hormone-fueled cancer in the disease’s early stages will be on hormone therapies like tamoxifen for several years. As for now, Fischer’s hair is growing back and ...

  6. List of selective estrogen receptor modulators - Wikipedia

    en.wikipedia.org/wiki/List_of_selective_estrogen...

    Sivifene (A-007) was initially thought to be a SERM due to its structural similarity to tamoxifen but it was subsequently found not to bind to the estrogen receptor (ER). [8] Tesmilifene (DPPE; YMB-1002, BMS-217380-01) is also structurally related to tamoxifen but similarly does not bind to the ER and is not a SERM. [9] [10]

  7. What Is Peyronie’s Disease? What You Need to Know, From ...

    www.aol.com/peyronie-disease-know-symptoms-risk...

    Tamoxifen. Typically used to treat breast cancer, tamoxifen has been shown to prevent the progression of Peyronie’s disease in vitro when combined with the ED medication tadalafil. The ...

  8. Estrogen deprivation therapy - Wikipedia

    en.wikipedia.org/wiki/Estrogen_deprivation_therapy

    Estrogen deprivation therapy, also known as endocrine therapy, is a form of hormone therapy that is used in the treatment of breast cancer.Modalities include antiestrogens or estrogen blockers such as selective estrogen receptor modulators (SERMs) like tamoxifen, selective estrogen receptor degraders like fulvestrant, and aromatase inhibitors like anastrozole and ovariectomy.

  9. Antihormone therapy - Wikipedia

    en.wikipedia.org/wiki/Antihormone_therapy

    Tamoxifen is also thought to lower the risk of breast cancer in those who have a predisposition or at risk. [9] Tamoxifen may be used in pre and postmenopausal women. [10] Toremifene is a similar SERM drug to tamoxifen, but is less common and only approved for treatment of metastatic cancer. Toremifene is generally prescribed once tamoxifen is ...