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Vitamin B12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. [2] It is one of eight B vitamins. It is required by animals, which use it as a cofactor in DNA synthesis, and in both fatty acid and amino acid metabolism. [3]
Impaired absorption of vitamin B 12 leads to pernicious anemia a type of megaloblastic anemia. Pernicious anemia comes about from the lack of gastric intrinsic factor produced by parietal cells in the stomach, and needed in the ileum for the absorption of vitamin B 12. Pernicious anemia is the most common cause of vitamin B 12 deficiency.
Cyanocobalamin is a form of vitamin B. 12 used to treat and prevent vitamin B. 12 deficiency except in the presence of cyanide toxicity. [7][8][2] The deficiency may occur in pernicious anemia, following surgical removal of the stomach, with fish tapeworm, or due to bowel cancer.
Registered dietitians explain what vitamin B12 is, how much you need, and the potential side effects of taking too much.
B12 deficiency is caused by a lack of dietary B12 or pernicious anemia, which affects B12 absorption. To treat a B12 deficiency, you may need to get B12 injections or take a supplement.
Supplements, Vitamin B-12 1,000 mcg With Folic Acid. ... Celiac disease, may benefit from B12 supplementation, as well as those individuals who are on medications that affect B12 absorption, says ...
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