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Atherosclerosis[ a ] is a pattern of the disease arteriosclerosis, [ 8 ] characterized by development of abnormalities called lesions in walls of arteries. This is a chronic inflammatory disease involving many different cell types, and driven by elevated levels of cholesterol in the blood. [ 9 ] These lesions may lead to narrowing of the ...
Cardiovascular disease (CVD) is any disease involving the heart or blood vessels. [3] CVDs constitute a class of diseases that includes: coronary artery diseases (e.g. angina, heart attack), heart failure, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, arrhythmia, congenital heart disease, valvular heart disease, carditis, aortic aneurysms, peripheral artery disease ...
Inclisiran, sold under the brand name Leqvio, is a medication used for the treatment of high low-density lipoprotein (LDL) cholesterol and for the treatment of people with atherosclerotic cardiovascular disease (ASCVD), ASCVD risk-equivalents, and heterozygous familial hypercholesterolemia (HeFH). [5][7][6][9] It is a small interfering RNA ...
August 28, 2024 at 11:33 AM. Novartis' Cholesterol-Lowering Drug Shows Encouraging Outcome In Late-Stage Study. Wednesday, Novartis AG (NYSE: NVS) released topline results from twice-yearly Leqvio ...
As noted by the American Heart Association, “atherosclerotic cardiovascular disease (ASCVD) is caused by the buildup of plaque within the arteries, limiting the flow of blood to important organs.”
Coronary artery disease (CAD), also called coronary heart disease (CHD), ischemic heart disease (IHD), [13] myocardial ischemia, [14] or simply heart disease, involves the reduction of blood flow to the cardiac muscle due to build-up of atherosclerotic plaque in the arteries of the heart. [5][6][15] It is the most common of the cardiovascular ...
Chronic fatigue immune dysfunction syndrome. CFS. Chronic fatigue syndrome. CGBD. Corticobasal ganglionic degeneration. CH. Cluster headache. CHARGE syndrome. Coloboma of the eye, heart defects, atresia of the nasal choanae, retarded growth & or development, genital abnormalities, ear abnormalities.
“Statins are typically used to manage high cholesterol in patients at elevated risk for atherosclerotic cardiovascular disease (ASCVD.) Generally speaking, a statin is started when a patient’s ...
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