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Smallpox was an infectious disease caused by variola virus (often called smallpox virus), which belongs to the genus Orthopoxvirus. [7] [11] The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, [10] making smallpox the only human disease to have been eradicated to date.
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Diseases associated with this genus include smallpox, cowpox, horsepox, camelpox, and mpox. [ 1 ] [ 2 ] The most widely known member of the genus is Variola virus , which causes smallpox. It was eradicated globally by 1977, through the use of Vaccinia virus as a vaccine .
The Massachusetts smallpox epidemic or colonial epidemic was a smallpox outbreak that hit Massachusetts in 1633. [1] Smallpox outbreaks were not confined to 1633 however, and occurred nearly every ten years. [2] Smallpox was caused by two different types of variola viruses: variola major and variola minor. [3]
The 1862 Pacific Northwest smallpox epidemic was a smallpox outbreak that started in Victoria on Vancouver Island and spread among the indigenous peoples of the Pacific Northwest Coast and into the indigenous peoples of the Northwest Plateau, killing a large portion of natives from the Puget Sound region to Southeast Alaska.
Smallpox was a dangerous disease caused by the variola major virus. The most common type of smallpox, ordinary, historically has devastated populations with a 30% death rate. The smallpox virus is transmittable through bodily fluids and materials contaminated with infected materials.
If the file has been modified from its original state, some details may not fully reflect the modified file. Short title V0031469 Gloucester smallpox epidemic, 1896
According to the Center for Disease Control, the rate for post-vaccination encephalitis following the smallpox vaccine is 3 to 12 per million, and the fatality rate is about 1 in a million. [16] (Since this was the largest vaccination campaign ever, it is likely to have contributed substantially to the C.D.C.'s data and estimates.)