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Classic Wickham's striae of non-erosive lichen planus in the left buccal mucosa (left cheek) Oral lichen planus (also termed oral mucosal lichen planus), is a form of mucosal lichen planus, where lichen planus involves the oral mucosa, the lining of the mouth. [39] This may occur in combination with other variants of lichen planus.
Wickham striae or Wickham's striae are whitish lines visible in the papules of lichen planus and other dermatoses, typically in the oral mucosa. [1] The microscopic appearance shows hypergranulosis. They are named after Louis Frédéric Wickham. [2] [3]
Louis Frédéric Wickham (28 February 1861 in Paris – 14 October 1913 in Mesnil-le-Roi) was a French physician and pathologist remembered for describing Wickham striae. [1] He trained in medicine in Paris, receiving his M.D. in 1890.
Desquamative gingivitis is a descriptive clinical term, not a diagnosis. [1] Dermatologic conditions cause about 75% of cases of desquamative gingivitis, and over 95% of the dermatologic cases are accounted for by either oral lichen planus or cicatricial pemphigoid. [1]
Wickham's striae: Louis Frédéric Wickham: dermatology: lichen planus: white or greyish lines on the lichen planus lesions Widal test: Georges-Fernand Widal: microbiology: enteric fever: serum agglutination; obsolete(?) Winterbottom's sign: Thomas Masterman Winterbottom: tropical medicine: trypanosomiasis: posterior cervical chain adenopathy
Oral lichen planus (OLP) is a chronic inflammatory T- cellular disorder that strikes the oral mucosa. In a clinical report in 2022, [28] a fast resolving of OLP was achieved in a patient treated with Abrocitinib. A dose of 200 mg of Abrocitinib was administered daily as monotherapy for twelve weeks.
Lichen planus Irregular epidermal hyperplasia with a jagged “sawtooth” appearance, compact hyperkeratosis or orthokeratosis, foci of wedge-shaped hypergranulosis, basilar vacuolar degeneration, slight spongiosis in the spinous layer, and squamatization. The dermal papillae between the elongated rete ridges are frequently dome shaped.
Lichenoid eruptions are dermatoses related to the unique, common inflammatory disorder lichen planus, which affects the skin, mucous membranes, nails, and hair. [74] [75] [76] Annular lichen planus Lichen planus actinicus; Atrophic lichen planus; Bullous lichen planus (vesiculobullous lichen planus) Erosive lichen planus