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Vascular risk factors can result in dysregulation of the neurovascular unit and hypoxia. Destruction of the organization of the blood–brain barrier, decreased cerebral blood flow, and the establishment of an inflammatory context often result in neuronal damage since these factors promote the aggregation of β-amyloid peptide in the brain. [37]
In brain tissue, a biochemical cascade known as the ischemic cascade is triggered when the tissue becomes ischemic, potentially resulting in damage to and the death of brain cells. Medical professionals must take steps to maintain proper CBF in patients who have conditions like shock, stroke, cerebral edema, and traumatic brain injury.
Fluid attenuated inversion recovery (FLAIR) vascular hyperintensity (FVH) is a radiographic marker seen on brain imaging in acute ischaemic stroke. FVH can be used as a proxy for slow leptomeningeal collateral blood flow, and may help reveal which areas of brain tissue are potentially salvageable. [12]
The trigeminovascular system (TVS) refers to neurons and their axonal projections within the trigeminal nerve that project to the cranial meninges and meningeal blood vessels [1] [2] residing on the brain's surface. [3]
The circle of Willis (also called Willis' circle, loop of Willis, cerebral arterial circle, and Willis polygon) is a circulatory anastomosis that supplies blood to the brain and surrounding structures in reptiles, birds and mammals, including humans. [1]
3D model of cerebral veins. In human anatomy, the cerebral veins are blood vessels in the cerebral circulation which drain blood from the cerebrum of the human brain.They are divisible into external (superficial cerebral veins) and internal (internal cerebral veins) groups according to the outer or inner parts of the hemispheres they drain into.
The brain pia mater is reflected from the surface of the brain onto the surface of blood vessels in the subarachnoid space. In the brain, perivascular cuffs are regions of leukocyte aggregation in the perivascular spaces, usually found in patients with viral encephalitis. Perivascular spaces vary in dimension according to the type of blood vessel.
It is a fragile portion of the brain that may be damaged leading to a germinal matrix hemorrhage (grade 1 intraventricular hemorrhage). Location/anatomy: The germinal matrix is next to the lateral ventricles (the "inside" of the brain). Function/physiology: Neurons and glia migrate radially outward from the germinal matrix towards the cerebral ...