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The goal of synthetic biology is to generate an array of tunable and characterized parts, or modules, with which any desirable synthetic biological circuit can be easily designed and implemented. [2] These circuits can serve as a method to modify cellular functions, create cellular responses to environmental conditions, or influence cellular ...
A logic translation is a translation of a text into a logical system.For example, translating the sentence "all skyscrapers are tall" as (() ()) is a logic translation that expresses an English language sentence in the logical system known as first-order logic.
In biology, translation is the process in living cells in which proteins are produced using RNA molecules as templates. The generated protein is a sequence of amino acids . This sequence is determined by the sequence of nucleotides in the RNA.
Initiation of translation is regulated by the accessibility of ribosomes to the Shine-Dalgarno sequence. This stretch of four to nine purine residues are located upstream the initiation codon and hybridize to a pyrimidine-rich sequence near the 3' end of the 16S RNA within the 30S bacterial ribosomal subunit . [ 1 ]
Translation is one of the key energy consumers in cells, hence it is strictly regulated. Numerous mechanisms have evolved that control and regulate translation in eukaryotes as well as prokaryotes. Regulation of translation can impact the global rate of protein synthesis which is closely coupled to the metabolic and proliferative state of a cell.
Translation promotes transcription elongation and regulates transcription termination. Functional coupling between transcription and translation is caused by direct physical interactions between the ribosome and RNA polymerase ("expressome complex"), ribosome-dependent changes to nascent mRNA secondary structure which affect RNA polymerase activity (e.g. "attenuation"), and ribosome-dependent ...
Tests of sufficiency in biology are used to determine if the presence of an element permits the biological phenomenon to occur. In other words, if sufficient conditions are met, the targeted event is able to take place. However, this does not mean that the absence of a sufficient biological element inhibits the biological event from occurring.
The modal depth of a formula also becomes apparent in the translation to first-order logic. When the modal depth of a formula is k, then the first-order logic formula contains a 'chain' of k transitions from the starting world . The worlds are 'chained' in the sense that these worlds are visited by going from accessible to accessible world.