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Penicillium chrysogenum (formerly known as Penicillium notatum) is a species of fungus in the genus Penicillium. It is common in temperate and subtropical regions and can be found on salted food products, [ 1 ] but it is mostly found in indoor environments, especially in damp or water-damaged buildings. [ 2 ]
Penicillium abidjanum [2] Penicillium adametzii [2] Penicillium adametzioides [2] Penicillium aeris [3] Penicillium aethiopicum [2] Penicillium albicans [2] Penicillium albidum [2] Penicillium albocoremium; Penicillium alexiae [4] Penicillium alfredii [5] Penicillium alicantinum [4] Penicillium allahabadense [6] Penicillium allii; Penicillium ...
The mould was identified as Penicillium chrysogenum and designated as NRRL 1951 or cantaloupe strain. [106] [116] The spores may have escaped from the NRRL. [117] [a] [b] Between 1941 and 1943, Moyer, Coghill and Raper developed methods for industrialized penicillin production and isolated higher-yielding strains of the Penicillium fungus.
The principal commercial strain of Penicillium chrysogenum (the Peoria strain) produces penicillin G as the principal component when corn steep liquor is used as the culture medium. [8] When phenoxyethanol or phenoxyacetic acid are added to the culture medium, the mould produces penicillin V as the main penicillin instead.
Penicillium chrysogenum is of major medical and historical importance as the original and present-day industrial source of the antibiotic penicillin. The species was considered asexual for more than 100 years despite concerted efforts to induce sexual reproduction.
In 1931, Thom re-examined different Penicillium including that of Fleming's specimen. He came to a confusing conclusion, stating, "Ad. 35 [Fleming's specimen] is P. notatum WESTLING. This is a member of the P. chrysogenum series with smaller conidia than P. chrysogenum itself."
Genome organization of Penicillium chrysogenum virus (PcV) [1] Genomes are linear double-stranded RNA which is around 12.5 kbp in length. The genome codes for four proteins. The genome has three double stranded RNA segments. All have extended highly conserved terminal sequences at both ends. [1] [3]
Penicillium tardochrysogenum is a filamentous species of fungus in the genus Penicillium which produces penicillin, secalonic acids D and secalonic acids F. [1] [2 ...