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Aducanumab, sold under the brand name Aduhelm, is a monoclonal antibody designed to treat Alzheimer's disease. [ 2 ] [ 3 ] It is a monoclonal antibody [ 3 ] [ 2 ] that targets aggregated forms (plaque) [ 4 ] [ 5 ] of amyloid beta (Aβ) found in the brains of people with Alzheimer's disease to reduce its buildup.
Aducanumab, sold under the brand name Aduhelm, is a monoclonal antibody designed to treat Alzheimer's disease. It is a monoclonal antibody that targets aggregated forms (plaque) of amyloid beta (Aβ) found in the brains of people with Alzheimer's disease to reduce its buildup. [10] It was developed by Biogen and Eisai. [11] Aducanumab is given via intravenous infusion. [5] Aducanumab was ...
The drug donanemab, which will be sold under the brand name Kisunla, is a monoclonal antibody infusion given every four weeks. ... Lilly said Kisunla will cost $32,000 for a 12-month supply.
This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.
AstraZeneca's rare diseases unit Alexion and Neurimmune - the firm behind the discovery of Biogen's Alzheimer's drug aducanumab - will work on evaluating a monoclonal antibody for the treatment of ...
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Crenezumab is a fully humanized monoclonal antibody against human 1-40 and 1-42 beta amyloid, which is being investigated as a treatment of Alzheimer's disease. [1] Crenezumab is highly homologous to solanezumab , another monoclonal antibody targeting amyloid-β peptides. [ 2 ]
The US Food and Drug Administration (FDA) label for donanemab contains a boxed warning about amyloid-related imaging abnormalities. [1]Side effects may include infusion-related reactions, with symptoms such as flu-like symptoms, nausea, vomiting and changes in blood pressure, and hypersensitivity reactions, including anaphylaxis (severe, life-threatening allergic reaction) and angioedema ...
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