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2. Temazepam - Wikipedia

   en.wikipedia.org/wiki/Temazepam

   The guidelines found that temazepam at a dose of 15 mg reduces sleep latency by 37 minutes (95% CI Tooltip confidence interval 21 to 53 minutes), increases total sleep time by 99 minutes (95% CI 63 to 135 minutes), and provides a small improvement to sleep quality. [19]

3. Benzodiazepine - Wikipedia

   en.wikipedia.org/wiki/Benzodiazepine

   The GABA A receptor is a protein complex located in the synapses between neurons. All GABA A receptors contain an ion channel that conducts chloride ions across neuronal cell membranes and two binding sites for the neurotransmitter gamma-aminobutyric acid (GABA), while a subset of GABA A receptor complexes also contain a single binding site for ...

4. GABA receptor agonist - Wikipedia

   en.wikipedia.org/wiki/GABA_receptor_agonist

   Gamma-aminobutyric acid, a GABA-B receptor agonist. A GABA receptor agonist is a drug that is an agonist for one or more of the GABA receptors, producing typically sedative effects, and may also cause other effects such as anxiolytic, anticonvulsant, and muscle relaxant effects. [1] There are three receptors of the gamma-aminobutyric acid. The ...

5. Somnifacient - Wikipedia

   en.wikipedia.org/wiki/Somnifacient

   Somnifacient (from Latin somnus, sleep [1]), also known as sedatives or sleeping pills, is a class of medications that induces sleep. It is mainly used for treatment of insomnia. Examples of somnifacients include benzodiazepines, barbiturates and antihistamines. Around 2-6% of adults with insomnia use somnifacients to aid sleep. [2]

6. Gabapentin - Wikipedia

   en.wikipedia.org/wiki/Gabapentin

   Specifically, it is a derivative of GABA with a pentyl disubstitution at 3 position, hence, the name - gabapentin, in such a way as to form a six-membered ring. After the formation of the ring, the amine and carboxylic groups are not in the same relative positions as they are in the GABA; [103] they are more conformationally constrained. [104]

7. Eszopiclone - Wikipedia

   en.wikipedia.org/wiki/Eszopiclone

   Overdoses of eszopiclone up to 90 times the recommended dose have been reported in which the patient fully recovered. [3] Fatalities have been reported only in cases in which eszopiclone was combined with other drugs or alcohol. [3] Overdose may be successfully treated with flumazenil, a GABA A receptor antagonist used also for benzodiazepine ...