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The Hill equation reflects the occupancy of macromolecules: the fraction that is saturated or bound by the ligand. [1] [2] [nb 1] This equation is formally equivalent to the Langmuir isotherm. [3] Conversely, the Hill equation proper reflects the cellular or tissue response to the ligand: the physiological output of the system, such as muscle ...
Hill's equation is an important example in the understanding of periodic differential equations. Depending on the exact shape of (), solutions may stay bounded for all time, or the amplitude of the oscillations in solutions may grow exponentially. [3] The precise form of the solutions to Hill's equation is described by Floquet theory. Solutions ...
However, a series of publications by Popova and Sel'kov [2] derived the MWC rate equation for the reversible, multi-substrate, multi-product reaction. The same problem applies to the classic Hill equation which is almost always shown in an irreversible form. Hofmeyr and Cornish-Bowden first published the reversible form of the Hill equation. [1]
Floquet theory shows stability in Hill differential equation (introduced by George William Hill) approximating the motion of the moon as a harmonic oscillator in a periodic gravitational field. Bond softening and bond hardening in intense laser fields can be described in terms of solutions obtained from the Floquet theorem.
Download QR code; Print/export Download as PDF; Printable version; In other projects ... move to sidebar hide. Hill equation may refer to Hill equation (biochemistry) ...
Although Hill's equation looks very much like the van der Waals equation, the former has units of energy dissipation, while the latter has units of energy. Hill's equation demonstrates that the relationship between F and v is hyperbolic. Therefore, the higher the load applied to the muscle, the lower the contraction velocity.
This median-effect equation, i.e. = where fa + fu = 1, is the unified form for the Michaelis-Menten equation for enzyme substrate saturation, the Hill equation for ligand occupancy at high order, the Henderson-Hasselbalch equation for pH ionization, and the Scatchard equation for the receptor binding. Thus, the half-affected (Dm) is equivalent ...
George William Hill (March 3, 1838 – April 16, 1914) was an American astronomer and mathematician. Working independently and largely in isolation from the wider scientific community, he made major contributions to celestial mechanics and to the theory of ordinary differential equations .