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The researchers isolated the virus from the brain, spinal cord, liver, lung, spleen, and kidney of a rat with symptoms of encephalitis and severe myelin injury, and gave it the strain name mouse hepatitis virus (MHV)-JHM. [7] MHV is now the most studied coronavirus in animals other than humans, [8] acting as a model organism for coronaviruses. [9]
Under ideal situations myoglobin will be filtered and excreted with the urine, but if too much myoglobin is released into the circulation or in case of kidney problems, it can occlude the kidneys' filtration system leading to acute tubular necrosis and acute kidney injury. Other causes of myoglobinuria include: McArdle's disease
The myoglobin is filtered by the kidneys, but is toxic to the renal tubular epithelium and so may cause acute kidney injury. [32] It is not the myoglobin itself that is toxic (it is a protoxin), but the ferrihemate portion that is dissociated from myoglobin in acidic environments (e.g., acidic urine, lysosomes). [citation needed]
13350 Ensembl ENSG00000185000 ENSG00000285482 ENSMUSG00000022555 UniProt O75907 Q9Z2A7 RefSeq (mRNA) NM_012079 NM_010046 RefSeq (protein) NP_036211 NP_034176 Location (UCSC) Chr 8: 144.31 – 144.33 Mb Chr 15: 76.39 – 76.4 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Diacylglycerol O -acyltransferase 1 is an enzyme that in humans is encoded by the DGAT1 gene. Function This gene ...
After testing the dye on mice tissue samples and raw chicken breast, the researchers rubbed the dye and water solution onto the skulls and abdomens of the mice. As the dye was absorbed, within a ...
Coronavirus diseases are caused by viruses in the coronavirus subfamily, a group of related RNA viruses that cause diseases in mammals and birds. In humans and birds, the group of viruses cause respiratory tract infections that can range from mild to lethal.
A large number of toxic plants may also cause symptoms. [87] Some agents are more specific to a certain species. Transmissible gastroenteritis coronavirus (TGEV) occurs in pigs resulting in vomiting, diarrhea, and dehydration. [88] It is believed to be introduced to pigs by wild birds and there is no specific treatment available. [89]
Rhabdomyolysis (shortened as rhabdo) is a condition in which damaged skeletal muscle breaks down rapidly, often due to high intensity exercise over a short period. [6] [4] [5] Symptoms may include muscle pains, weakness, vomiting, and confusion.