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The spinal canal may become narrowed due to abscesses, granulation tissue, or direct dural invasion resulting in compression of cord and neurological deficits. [3] Kyphosis is a result of the front of the spine collapsing. Injury to the thoracic spine are more likely to result in kyphosis compared to lumbar spine injuries. [3]
Tuberculosis generally affects the lungs, but it can also affect other parts of the body. [1] Most infections show no symptoms, in which case it is known as latent tuberculosis . [ 1 ] Around 10% of latent infections progress to active disease that, if left untreated, kill about half of those affected. [ 1 ]
One of the most prominent causes of Fibrous anklylosis is physical trauma. [4] After experiencing a severe physical injury, the body will try to recover by activating it's mensenchymal stromal cells (MSCs), a type of stem cells that can differentiate into different cells such as osteoblasts, chondrocytes, and other factors such as bone matrix/growth factors that are used to stimulate growth ...
In addition to tuberculosis, other possible causes of gibbus deformity include pathological diseases, hereditary and congenital conditions, and physical trauma to the spine that results in injury. [ 6 ] [ 7 ] Gibbus deformity may result from the sail vertebrae associated with cretinism (the childhood form of hypothyroidism ...
Mycobacterium tuberculosis is the most common cause of both pulmonary tuberculosis and tuberculous lymphadenitis. [1] [6] Historically, transmission of Mycobacterium bovis from dairy consumption was another frequent cause of tuberculous lymphadenitis, but incidence has drastically decreased in developed countries since the advent of pasteurization and other efforts to prevent bovine ...
Symptoms may include pain in a specific bone with overlying redness, fever, and weakness. [1] The feet, spine, and hips are the most commonly involved bones in adults. [2] The cause is usually a bacterial infection, [1] [7] [2] but rarely can be a fungal infection. [8] It may occur by spread from the blood or from surrounding tissue. [4]
Multiple bones are involved in children and usually only a single bone is involved in adults suffering from tuberculous dactylitis. [2] Tuberculous dactylitis affects the short tubular bones of the hands and feet in children. It often follows a mild course without fever and acute inflammatory signs as opposed to acute osteomyelitis. There may ...
It is possible that, following an initial tuberculosis infection resulting in bacteremia, a foci of granulomatous inflammation may coalesce into a caseous tuberculoma. [20] Pulmonary tuberculomas may arise due to repeated cycles of necrosis and re-encapsulation of foci, or, alternatively, the shrinkage and fusion of encapsulated densities.